Research Officer – Neuroendocrinology Group

Job No: GC201965
Location: Darlinghurst, NSW

Garvan is about changing the practice of medicine and has embraced genomics to drive this change. In the last 10 years, a million-fold improvement in the speed and cost of sequencing genomes has transformed our field, and more recently magical advancements have made doing genomics at the level of individual cells a reality.

The field of study of The Neuroendocrinology Group, led by Dr Yanchuan Shi, is geared toward major contemporary health issues: obesity and obesity-related diseases such as diabetes and cancer. Our research focusses on understanding how adipose tissue (white & brown), insulin secretion and energy & glucose homeostasis are regulated in healthy and diseased states with the view to identify safer and more effective therapeutic options for obesity and diabetes interventions.  

The Opportunity

The Research Officer will investigate the underlying molecular mechanisms that contribute to the development of diabetes and obesity employing unique animal models and state-of-the-art technologies in metabolic and neuroscience research.

The key responsibilities include:

  • Designing and managing own experiments and report and discuss findings back to supervisor
  • In vivo and in vitro analysis of various knockout/knockin mouse models using physiological, cell culture and immunohistochemical techniques
  • Being responsible for the writing of manuscripts, with an emphasis on submissions to high quality journals
  • Making significant contributions to preparing and submitting grant and fellowship proposals with a view to eventual self-funding
  • Oversight of biological colonies and breeding plans
  • Maintaining animal and human ethics protocols (submission, compliance and annual reports, etc)
  • Proactively managing the administrative functions associated with lab management
  • All staff are required to comply with Garvan’s Work Health & Safety (WHS) Policy and work in accordance with the WHS management system at all times

About you: 

You will have the following key skills and experience:


  • A tertiary qualification in health/ laboratory science, a PhD in obesity, diabetes, metabolism or neuroscience research fields or a relevant field;
  • Ability to write and communicate in the form of published first author research papers;
  • Excellent written and oral communication skills;
  • Previous experience with phenotypic characterization of mouse models;
  • Expertise and experience with molecular and cell biology techniques;


  • Expertise with primary cell isolation (eg. adipocytes and/or pancreatic islets) and ex vivo and in vitro cell culture and assays;
  • Demonstrated experience with RNA-seq and/or proteomics analysis using bioinformatic tools;
  • Previous experience with grant writing and ethics applications;
  • Experience with management of research animal breeding colonies


How to Apply:

All applications must be submitted via the Garvan Careers site via the link below. Applications from other sites/channels will unfortunately not be considered. 

 Please include the following in your application:

  • A cover letter
  • Your resume including at least 2 referees
  • Copies of relevant qualifications / academic transcripts

Only applicants with working rights in Australia are eligible to apply for this role.

This full-time position is offered on a 1-year term in the first instance with potential to extend.


Closing Date:

The position will remain open until filled.


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