Development Bioinformatician

Job No: GC201882
Location: Darlinghurst, NSW

In 2017, the Garvan Weizmann Centre for Cellular Genomics (GWCCG) was formed, bringing together the Garvan Institute of Medical Research and The Weizmann Institute of Science to build Australia’s first Centre for Cellular Genomics.

The Garvan and the Weizmann Institutes have harnessed their synergistic strengths (in cytometry, genomics, informatics, and data visualisation) to enable cellular and single cell genomics to become routine tools for clinical and scientific analysis of many disease states. The Centre has a specific focus on 1) application of genomics (including DNA, transcriptomics, and epigenomics) to understand the cellular processes of the brain, immune system, and cancer; 2) the diagnosis of genetic diseases, stratification of cancers, and avoidance of adverse drug reactions; 3) the advancement of personal genetic health; and 4) the development of an improved health system that uses targeted information at cellular level to improve outcomes for patients and to better focus healthcare expenditure.

The Opportunity

The Development Bioinformatician will oversee the creation of new computational methods and tools to solve problems arising from new single cell assays being developed in GWCCG. There will be a particular focus on single cell DNA sequence data, as well as multi-level genomics data from individual cells. The role will also focus on supporting large-scale research activities undertaken by GWCCG researchers, or in collaboration with external researchers.

Reporting to the Head of GWCCG Dr Joseph Powell, the key responsibilities include:

  • Development of new methods for processing and integrating high-throughput single cell sequence data generated from new molecular assays
  • Work closely with the GWCCG Production Bioinformatician to help translate the new computational techniques from a research setting to production scale tools
  • Work closely with Garvan’s Data Intensive Computer Engineering (DICE) group regarding the building of software pipelines that will run on DICE’s HPC and OpenStack computing environment, Australia’s supercomputing facility, the National Computational Infrastructure (NCI), as well as on commercial clouds (AWS, Google, and Azure)
  • Take the lead in delivering research output and writing scientific papers arising from research conducted in GWCCG
  • Play a role in writing funding and grant proposals
  • Assist collaborators in data analysis and to check the validity of experimental design and results
  • Represent GWCCG at national and international conferences, engaging with the research and clinical community, and promote the expansion of GWCCG through participation outreach initiatives

This role is offered on a full-time basis for 2 years in the first instance.

About You

You will have the following key skills and experience:

  • The Bioinformatician shall possess a PhD or higher degree in a relevant area of science or informatics (exceptional candidates with a MSc will be considered)
  • Expertise in computational bioinformatics techniques, with a special focus on single cell transcriptomics, genomics and epigenetics
  • Demonstrated experience in bioinformatics research and a proven track record in translating research through activities such as peer-reviewed publications
  • Experience working in genome informatics in either a research or commercial setting is highly desirable
  • Demonstrated experience in working in high performance computing environments
  • Very strong programming skills in languages such as C/C++, Python, Perl, and R
  • Demonstrated experience in using version control and software repositories
  • Demonstrated experience in project management methodology including planning, implementation and reporting, and the ability to assess priorities and manage competing deadlines
  • Excellent written and oral communication, representation and interpersonal skills essential for interaction with internal and external stakeholders, including GWCCG Executives

How to Apply

All applications must be submitted via the Garvan Careers site via the link below. Applications from other sites/channels will unfortunately not be considered.

http://garvan.applynow.net.au/jobs/GC201882  

Your application should include: 

  • A cover letter
  • Your resume including at least 2 referees
  • Copies of relevant qualifications / academic transcripts

Only applicants with full working rights in Australia are eligible to apply for this role.

Closing Date

As we are reviewing applications as they are received, we encourage you to submit your application as soon as possible.

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